Kaede Akamatsu (code name: Noir) is the Ultimate Pianist at the Ultimate Academy for Gifted Juveniles and a participant in the Killing School Semester. She serves as a member of the Phantom Thieves of Hearts (2nd Gen), an organization affiliated with the Kirijo Group. Kaede is also close friends with Ayanno Yoshizawa (Violet) and Shuichi Saihara (the Ultimate Detective).

Miyano Yoshikazu (code name: Fox) is a student at Hope's Peak Academy with the title of Ultimate ???. He serves as a second-in-command for the Phantom Thieves of Hearts (2nd Gen) under the Kirijo Group. He is close friends with Ayanno Yoshizawa and harbors a crush on Kaede Akamatsu (Noir). Characterized as kind-hearted, straightforward, and passionate, Miyano is quiet and reserved but possesses a firm, confident voice when necessary. Highly approachable and deeply caring, he quickly bonds with others and consistently prioritizes their well-being.

Sorey is boy, who has a kind heart, an honest expression, and a positive outlook on life. He lives in Elysia, the village of seraphim, and is the only human among them. Unlike most humans, Sorey has the resonance to see seraphim and is childhood friends with a Water seraph, Mikleo. As a child, he came into the possession of a book called the Celestial Record, and from that point, he has had a fascination with ancient ruins. Sorey later enters into a contract with Lailah to become a Shepherd.

Lailah is a Fire seraph. She has been living in the Sacred Blade for a long time, waiting for a new Shepherd to appear. Her true name is Fethmus Mioma, meaning "Lailah the Pure".

Edna is an Earth seraph and the younger sister of Eizen. She distrusts humans and behaves mostly apathetic, but will become emotional when the situation involves her only living family member, her older brother. Her true name is Hephsin Yulind, meaning "Early-Bloomer Edna".