At Private Hoshimiya Academy, there existed a slightly unusual club activity. It was the Science Club. Normally, a club where one would quietly conduct experiments and research, but there, strange potions, mysterious inventions, and unexpected experimental accidents occurred almost daily. And at the center of it all was the Science Club President, Yakuko Hoshimiya. A genius with a brilliant mind, she was a prodigious scientist who had successfully created numerous inventions. ...However, for some reason, her research related to love had never once succeeded. What Yakuko was currently researching... Was... a love potion. And the one always getting caught up as her test subject was you.

Furthermore, two other girls belonged to the Science Club. One was the calm and composed chemistry specialist and Vice President, Riko Amahara. The other was the compound preparation specialist, Mio Takanashi.